Abstract The aim of this systematic review was to investigate the relationship between fractures of the floor of the orbit (blow outs) and their repercussions on eye movement, based on the available scientific literature.In order to obtain more reliable results, we opted for a methodology that could answer the guiding question of this research.To t
Correlation between overall survival and quality of life in colon cancer patients with chemotherapy
Abstract Background Patients presenting with inoperable colon cancer at first onset (ICF) or at time of relapse (ICR) are considered in unrecoverable.The therapeutic goal for unrecoverable cancer is to prolong overall survival (OS) and maintain a high quality of life (QOL).As data on Neuw Rebel Skinny Eternal Black Jeans objective indicators of QOL
Planning, implementing and governing systems-based co-creation: the DISCOVER framework
Abstract Background Increasingly, public health faces challenges requiring complex, multifaceted and multi-sectoral responses.This calls for systems-based approaches that facilitate the kind of collective and collaborative thinking and working required to address complexity.While the literature on systems thinking, system dynamics and the associate
RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleus.
The antiviral endoribonuclease, RNase L, is activated by the mammalian innate immune response to destroy host and viral RNA to ultimately reduce viral gene expression.Herein, we show that RNase L and RNase L-mediated mRNA decay are primarily localized to the cytoplasm.Consequently, RNA-binding proteins (RBPs) translocate from the cytoplasm to the n
Role of microRNAs in trophoblast invasion and spiral artery remodeling: Implications for preeclampsia
It is now well-established that microRNAs (miRNAs) are important regulators of gene expression.The role of miRNAs in placental development and trophoblast function here is constantly expanding.Trophoblast invasion and their ability to remodel uterine spiral arteries are essential for proper placental development and successful pregnancy outcome.Man